An official website of the United States government

Official websites use .gov

A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS

A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

You are viewing ARCHIVED CONTENT released online from January 20, 2017 to January 20, 2021.

Content in this archive site is NOT UPDATED, and links may not function.

For current information, go to

PEPFAR-supported smiling group of women in Mozambique [Sarah Day Smith/PEPFAR US Embassy Maputo]

About Us – PEPFAR

Share this page on:

Who We Are

The U.S. President’s Emergency Plan for AIDS Relief (PEPFAR) [866 KB] is the largest commitment by any nation to address a single disease in history, enabled by strong bipartisan support across nine U.S. congresses and three presidential administrations, and through the American people’s generosity.  PEPFAR shows the power of what is possible through compassionate, cost-effectiveness, accountable, and transparent American foreign assistance. 

Under the leadership of Ambassador-at-Large, Deborah L. Birx, M.D., PEPFAR is managed and overseen by the U.S. Department of State’s Office of the U.S. Global AIDS Coordinator and Health Diplomacy. PEPFAR leverages the power of a whole-of-government approach to controlling the global HIV/AIDS epidemic, implemented by seven other U.S. government departments and agencies:  the U.S Agency for International Development ; the U.S. Department of Health and Human Services  and its agencies, including the Centers for Disease Control and Prevention , Health Resources and Service Administration, and the National Institutes of Health; the U.S. Department of Defense ; the Peace Corps ; the U.S. Department of Labor; the U.S. Department of Commerce; and the U.S. Department of the Treasury. 

OGAC organization chart

What We Do

Since its inception in 2003, PEPFAR has invested over $85 billion in the global HIV/AIDS response, saving over 18 million lives, preventing millions of HIV infections, and accelerating progress toward controlling the global HIV/AIDS epidemic.

The PEPFAR Strategy For Accelerating HIV/AIDS Epidemic Control (2017-2020) [3 MB] provides a road map for accelerated implementation at scale in 13 high-burden countries with the greatest potential to achieve HIV/AIDS epidemic control by 2020. The Strategy also reaffirms PEPFAR’s continued support for more than 50 countries worldwide and our commitment to ensure all populations, including key populations and other vulnerable groups, can access HIV services. 

PEPFAR’s strategic rigor has allowed the program to significantly expand its lifesaving results [856 KB] and impact without increased financial resources over the past nine years. 

PEPFAR funding graph

PEPFAR’s investments also have strengthened the systems that drive effective, efficient, and sustainable health care. These investments create a lasting health system for partner countries to confront other current and future health challenges, enhance global health security, and protect America’s borders.

PEPFAR’s transformative, lifesaving impact is unassailable, but our mission is not yet finished. The HIV pandemic continues to evolve in every community and country and PEPFAR constantly adapts to address new risk groups, new health challenges, and persistent gaps.

Discover More

U.S. Department of State

The Lessons of 1989: Freedom and Our Future